There are some normal effects of aging on the brain that everyone experiences - forgetfulness, learning new things is a little more difficult, it takes longer to recall information like names and dates. For people who develop Alzheimer’s Disease, the effects are more severe and there are more of them. Alzheimer’s is a form of dementia that directly impacts behavior, memory, and thought processes.
Possible contributing factors to developing Alzheimer’s are believed to be a long history of high blood pressure, a history of head trauma, genetic predisposition, and elevated homocysteine levels. Women are more likely to develop Alzheimer’s because they tend to live longer, which gives them more time to develop the disease.
As Alzheimer’s progresses, symptoms increase and become more severe. At first, it is often difficult to distinguish lzheimer’s from the normal effects of aging. Symptoms in the first stage include repeating statements and questions, difficulty naming familiar objects, changes in personality, loss of interest in activities enjoyed before, frequently misplacing things, and getting lost on familiar routes. Symptoms become more obvious as the disease advances. Symptoms that are already present become more severe and new symptoms can include forgetting events from personal history, hallucinations, difficulty performing every day tasks, forgetfulness about recent events, and difficulty selecting appropriate attire. In the final stages of Alzheimer’s, symptoms are the most severe. People in the end stages of Alzheimer’s lose the ability to understand language, do not recognize family members like spouses and children, and cannot perform basic tasks independently like eating, bathing, and getting dressed.
These symptoms and more are caused by physiological changes in the brain. As the disease progresses, communication between the different parts of the brain are disrupted by neuritic plaques, neurofibrillary tangles, and senile plaques. Neuritic plaques are clusters of nerve cells that are dead or dying, other brain cells, and protein that form in the brain. Neurofibrillary tangles are twisted protein fragments that clog the nerve cells from within. Senile plaques the byproducts of nerve cells dying have accumulated with protein fragments. These build ups in the brain disrupt the neural transmissions that make it possible for us to think, speak, move, and function in general. While these may be found in any aging brain, they are found in very high levels in a brain suffering from Alzheimer’s.
There is no cure for Alzheimer’s, nor is there a proven method of prevention. Studies performed on preventing Alzheimer’s have been inconsistent and inconclusive. It is beleived that a healthy lifestyle that includes a well balanced diet, no smoking, and regular physical exercise can all at the very least help delay the onset of Alzheimer’s. Some studies have indicated that folic acid, vitamins B3, B12, and C, as well as the spice turmeric may all help prevent the accumulative damage to the brain that is associated with Alzheimer’s. Regular participation in intellectual activities like crossword puzzles, board games, strategy games, playing a musical instrument, and learning a language can all help minimize the build up of the tangles and plaques that are the root of the Alzheimer’s disease symptoms. Even if all these steps do not help prevent the onset of Alzheimer’s, they can’t hurt either.
The onset and progression is a frightening and frustrating experience for the person suffering from it as it is for the people close to the affected person. In the years since it was first discovered by Dr. Alzheimer in 1906, support groups have developed for both the people suffering from it and their family members.
Here are some useful web sites for learning more about Alzheimer’s and finding support: